Showing posts with label Flu. Show all posts
Showing posts with label Flu. Show all posts

Thursday, October 22, 2020

Fujifilm partners with Shanghai firm to seek China COVID-19 approval for Avigan

TOKYO— Japan's Fujifilm Holdings Corp said on Thursday it has partnered with Shanghai-based Carelink Pharmaceutical Co to seek approval in China for Avigan to treat COVID-19 and influenza.

Carelink will use Fujifilm's data on Avigan's treatment of novel coronavirus infections and influenza to seek imported drug approval in China, Fujifilm said in a statement. The two companies also plan to develop an injectable form of the drug.

Fujifilm said last week it was seeking approval for Avigan as a treatment for COVID-19 in Japan. That followed results from a late-stage study in Japan that showed the antiviral drug reduced recovery time for patients with non-severe symptoms.

Avigan, originally developed as an emergency flu drug and known generically worldwide as favipiravir, has been approved in India and Russia to treat COVID-19.

Fujifilm sold global rights in July on Avigan to India's Dr Reddy's Laboratories and Dubai-based Global Response Aid. That deal excluded China, Japan and Russia.

Last month, Fujifilm said the late-stage study of 156 COVID-19 patients in Japan showed that symptoms of those treated with Avigan improved after 11.9 days, versus 14.7 days for a placebo group.

Results of the study, conducted by subsidiary Fujifilm Toyama Chemical, were found to be statistically significant. 

-reuters-

Friday, April 3, 2020

Japan mulls offering anti-flu drug Avigan to nations fighting coronavirus


The Japanese government is considering offering the anti-influenza drug Avigan for free to countries looking to use it to treat new coronavirus patients, its top government spokesman said Friday.

"Some 30 countries have made requests through diplomatic channels to Japan for the procurement of Avigan," Chief Cabinet Secretary Yoshihide Suga said at a press conference. The drug developed by a group firm of Fujifilm Holdings Corp. is seen as effective in treating the COVID-19 disease caused by the virus.

"We intend to expand clinical research on Avigan with countries wishing to cooperate," Suga said.

Prime Minister Shinzo Abe told a press conference last Saturday that the government will push the development of drugs and vaccines, including Avigan, to fight the pneumonia-causing coronavirus.

Fujifilm Toyama Chemical Co. said Tuesday it has started clinical tests to evaluate the efficacy of the drug, also known as Favipiravir, to COVID-19 patients.

On Thursday, the German health ministry said it will seek to purchase Avigan tablets as a treatment drug for the new coronavirus. Local media said the ministry will buy several million tablets to treat patients with severe symptoms.

A study by researchers at Wuhan University and other institutions in China has shown cases in which Avigan was effective against the coronavirus, especially for the treatment of those with mild symptoms.

Avigan has been manufactured and stocked in Japan as an anti-influenza drug. There is hope it can also help treat other diseases, including Ebola, as well as a tick-borne illness.

Kyodo News

Wednesday, January 22, 2020

Thailand finds fourth China coronavirus infection


BANGKOK - Thailand has quarantined a fourth patient with the new coronavirus including 1 Thai national, authorities said on Wednesday, days before the Lunar New Year holiday when thousands of Chinese tourists are expected to arrive.

Nine people have died from the flu-like coronavirus in China, with 440 confirmed cases, most in the central city of Wuhan where the virus first appeared late last year.

The Thai patient, a 73-year-old woman, had traveled to Wuhan during the New Year holidays and developed a fever after returning, the Public Health Ministry said.

She was being monitored in a separate ward in a hospital in Nakhon Pathom, 60 km west of Bangkok, where her condition was gradually improving, it added.

"We can control the situation. There have not been cases of human-to-human transmission in Thailand because we detected the patients as soon as they arrived," Public Health Minister Anutin Charnvirakul told reporters.

Two other Chinese patients had recovered and been sent home while a third would return once tests showed he was clear of the virus, Anutin said.

Thai officials were stepping up screening at airports to look for passengers with high body temperatures, coughs, headaches and trouble breathing, police said.

The virus has spread to other cities including Beijing and Shanghai, as well as the United States, South Korea, Japan and Taiwan.

source: news.abs-cbn.com

Saturday, January 12, 2013

Flu reaches epidemic level in US - CDC

Influenza has officially reached epidemic proportions in the United States, with 7.3 percent of deaths last week caused by pneumonia and the flu, the U.S. Centers for Disease Control and Prevention said on Friday.

The early start and fast spread of flu this season - especially after 2011-2012's very mild outbreak - has overwhelmed doctors' offices and hospitals, forcing some patients to wait through the night to be seen in emergency departments.

Nine of the 10 U.S. regions had "elevated" flu activity last week, confirming that seasonal flu has spread across the country and reached high levels several weeks before the usual late January or February, CDC reported.

Only one region - the Southwest and California - had "normal" flu activity last week.

Tens of thousands of Americans die every year from flu, even in non-epidemic years. The threshold for an epidemic is that it causes more than 7.2 percent of deaths, but as yet there is no definitive count of the total caused by flu this year.

In Boston, flu cases are 10 times higher than they were last year, causing Mayor Thomas Menino to declare a public health emergency on Wednesday.

In Illinois, 24 hospitals struggling to cope with the flood of flu cases had to turn away people arriving in the emergency department, while in Pennsylvania, the Lehigh Valley Hospital outside Allentown has set up a tent for people who arrive with less-severe flu.

A total of 20 children have now died from this season's flu, up two from the previous week, the CDC said. That compares to 34 during the full 2011-2012 flu season and 282 during the severe 2009-2010 season.

The outbreak has led to attempts at prevention that go beyond the standard advice of getting vaccinated, avoiding contact with sick people and frequently washing hands with soap.

In Boston, the Catholic Archdiocese has told priests they could suspend the offering of communion wine using a shared chalice and bow rather than shake hands while exchanging the Sign of Peace, a Christian greeting.

Auxiliary Bishop Robert P. Deeley urged priests to use hand sanitizer before and after communion and to avoid touching congregants' tongues or hands. He said parishioners who were ill "should remain at home and return to church when they are well."

'MODERATELY EFFECTIVE' VACCINE

While flu vaccines offer protection, they are not failsafe.

This year's flu vaccine is 62 percent effective, scientists reported on Friday in the CDC's weekly publication, meaning that almost four in 10 people who receive the vaccine and are exposed to the virus will nevertheless become infected.

This is considered "moderate" effectiveness and is in line with previous years' flu vaccines, which range from 50 percent to 70 percent effective, Dr. Joseph Bresee, chief of the CDC's influenza division, told reporters.

Experts recommend the vaccine for everyone over 6 months of age. Even if it does not prevent flu, immunization can reduce the severity of the illness, preventing pneumonia and other life-threatening results of flu.

Public health authorities were correct in their forecast of which flu strains would emerge this season and therefore what vaccine to make: one that contains two strains of influenza A and one strain of influenza B. An A strain, called H3N2, predominates this season, though the B strain has caused about 20 percent of cases.

About 10 percent of cases have been caused by a B strain that is not in the vaccine, which "has space for only three strains," CDC Director Dr. Tom Frieden said.

Dr. Arnold Monto of the University of Michigan, a co-author of the vaccine-effectiveness study told Reuters this year's vaccine was "a good vaccine, but not a great vaccine."

It is less effective for the frail elderly, for people receiving chemotherapy for cancer, and for people taking oral steroids, as their immune systems have been weakened and are often unable to produce an effective number of antibodies in response to the vaccine.

One reason flu vaccines are far from perfect, said Monto, is where in the body the viruses find a home - congregating on the surface of small airways in the respiratory tract, while virus-fighting antibodies that are stimulated by vaccines mostly stay in the bloodstream.

According to the most recent CDC data, 37 percent of Americans - 112 million people - had received the flu vaccine as of mid-November.

Of the 135 million doses produced this year, 128 million have been distributed to doctors' offices, drug stores, clinics and other facilities.

Although public health officials believe enough doses were produced, some spot shortages have developed. "You may have to call a few places," before finding one with vaccine, said the CDC's Bresee, "but it should be available."

MAY HAVE PEAKED


In its weekly flu update on Friday, the CDC reported that 24 of the 50 U.S. states as well as New York City had experienced "high activity" in flu-like illnesses last week. In 16 states, activity was moderate, while in 10 it was low or minimal.

The 24 states reporting high activity was down from 29 the previous week, raising hopes that the disease may have peaked in some regions, particularly the Southeast, and that a flu season that began early may also end early. It typically starts in December, peaks in January or February and peters out by late March or early April.

The percentage of visits to healthcare providers last week for flu-like illness - 4.3 percent - is comparable to that during the 2007-2008 flu season, which was characterized as "moderately severe" but which peaked some two months later. By comparison, in the 2009 H1N1 "swine" flu pandemic, 7.7 percent of visits were for flu-like illness.

source: abs-cbnnews.com

Sunday, February 19, 2012

Flu season has peaked nationwide, say health officials

TOKYO — The National Institute of Infectious Diseases said Saturday that it believes this year’s flu season has peaked.

The institute said that as of Friday, the number of flu patients who were seen per medical facility averaged 40.34, which it estimates was a decrease of around 100,000 cases from the week before, Fuji TV reported. According to the institute’s estimates, around 2,010,000 people were infected in that week.

The institute added that although the general national trend is downward, cases are still on the increase in certain areas, such as Kagoshima Prefecture.

The Ministry of Health, Labor and Welfare is urging people to continue to take precautions against infection, such as keeping rooms humid, washing hands thoroughly and gargling regularly.

This winter, most patients tested were found to have been infected by the A strain of the virus, known in Japan as the “Hong Kong” strain.

The institute added that it believes one of the causes of the large number of infections this year may have been the unusually high number of low-humidity days, which create conditions in which it is easier for the virus to attach itself to the mucous membrane in the throat.

source: japantoday.com